AP Biologyhardmcq1 pt

During mitosis, a cell undergoes a series of coordinated events to ensure accurate chromosome segregation. Which of the following is a critical checkpoint that regulates this process?

A.A) The metaphase checkpoint, which ensures that chromosomes are aligned at the spindle equator.

B.B) The G2/M checkpoint, which allows the cell to halt cell cycle progression if DNA damage is detected.

C.C) The anaphase checkpoint, which prevents sister chromatids from separating prematurely.

D.D) The telophase checkpoint, which ensures that the nuclear envelope reforms properly after mitosis.

Explanation

Core Concept

The metaphase checkpoint is a critical step in mitosis that ensures chromosomes are aligned at the spindle equator before sister chromatids separate. This is essential for accurate chromosome segregation and preventing chromosomal abnormalities. (Concept: Mitosis) The primary reason this is true is that improper alignment of chromosomes can lead to errors in segregation and result in abnormal offspring cells.

During mitosis, a cell undergoes a series of coordinated events to ensure accurate chromosome segregation. Which of the following is a critical checkpoint that regulates this process?

Explanation

Core Concept

Correct Answer